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The Consumer Guide to Multi-Vitamins In This Guide...
  Why Are They Needed?
  Benefits and Uses
  Daily Requirements
  Deficiency Risk Factors
  Optimal Intake
  Safety
  References
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Why are They Needed? Human bodies cannot function without protein, carbohydrates (sugars and starches) and fats—or the nutrients we call vitamins and minerals.

Because vitamins and minerals are not evenly distributed among foods, people need to eat a well-balanced diet, high in "nutrient-dense" fruits, vegetables, nuts, seeds, and whole grains.

However, few people eat the kind of varied, plant-rich diet needed to provide optimal—or even minimal—levels of all vitamins and minerals. And, modern farming techniques drain the soil of nutrients, making our fruits and vegetables less nutritious. (This is one reason for the popularity of produce grown in nutrient-rich organically cultivated soils.) The facts speak for themselves:

  • In the most recent USDA survey, more than 80 percent of women and more than 70 percent of men consumed less than two-thirds of the RDA for one or more nutrients. People are eating almost 20 percent more vegetables than they did 25 years ago. But 25 percent of the vegetables consumed in the U.S. are artery clogging French fries, according to a study reported in the journal Cancer.
  • While there is no clear evidence that daily multi-vitamins extend the life spans of healthy people, there is considerable evidence that they can reduce the risks of specific diseasesthereby increasing "health span."
  • Americans and western Europeans are commonly considered the best-fed people in the world. But this characterization is accurate only in reference to caloric intake. In fact, most are overfed and undernourished, eating too much fat, sugar, refined flour, and "empty-calorie" foods.
  • A recent report on children's eating habits indicates that "low nutrient-density foods"—including cake, cookies, donuts, and sugary fruit drinks—are major components of U.S. children's diets, and notes "this compromises intakes of more nutritious foods and may impede compliance with current dietary guidelines."
  • Americans rank 17th in terms of life expectancy or that they are spending billions of dollars each year to treat illnesses directly related to poor nutrition. The $666 billion spent to treat disease in 1990 represented an expenditure of $2,566 per year for every man, woman, and child.

Benefits and uses: Proof that multivitamin-mineral supplements protect health continues to accumulate:
Taking a multi-vitamin pill for 15 years of more may reduce the risk of colon cancer by 75 percent, according to a study of 80,000 U.S. nurses.

Daily doses of multivitamin supplements have been found to cut fetal deaths, low birth weight, and pre-term births by 40 percent.
After years of foot-dragging in the face of persuasive evidence, in 1997 the U.S.FDA finally agreed that women who intend to become pregnant should be getting 400 mcg of supplemental folic acid (a B vitamin) per day, to reduce the risk of severe birth defects. The only way to ensure this intake level is to consume vitamin supplements or folate-fortified foods.

Studies show that women with the highest intake of folate and vitamin B6 may cut their heart disease risk in half compared to women with the lowest intake. Men and women taking levels of Vitamin E higher than can be obtained from food have lower rates of heart disease than those who ingest low doses do. (Over 800,000 Americans die of heart disease every year.)

Daily multivitamin supplements have been found to boost immune response by up to 60% in older people; Vitamin E supplementation has also been found to boost immune response in the elderly. One clinical trial indicates that nutritional supplements could halve the rate of infectious diseases among elderly persons.

Elderly users of both vitamin E and vitamin C supplements were found to have a 42 percent decreased risk of mortality compared to non- users.

Researchers estimate that regular use of vitamin supplements, including vitamin C and vitamin E could delay the onset of cataracts by at least ten years.

Many studies indicate that increased intake of vitamins A, C, E, and other nutrients, in excess of the RDA, reduce the risk of cancer, which causes 500,000 American deaths each year.

Daily requirements: The best way to get your vitamins and minerals is through food. The only problem is, it's nearly impossible to get the optimal amounts of vitamins and minerals from your diet, no matter how good it is. And "optimal" doesn't mean the RDAs. The RDAs (Recommended Daily Allowances) were created as guidelines to vitamin and mineral requirements for healthy people, the average amount adequate to prevent deficiency diseases. They do not represent the amounts most researchers now believe are needed to achieve optimal health and help prevent a variety of diseases.

Vitamins and Minerals RDA for Men RDA for Women* Optimal Adult Intake Maximum Safe Intake for Healthy Adults†††

Vitamin A

5,000 IU

4,000 IU

10,000 IU

25,000 IU††

Thiamin

1.5 mg

1.1 mg to 1.5 mg

100-300 mg

No known limit

Riboflavin

1.7 mg

1.3-1.7 mg

100-300 mg

No known limit

Niacin

19 mg

15-19 mg

50-100 mg#

No known limit

Vitamin B6

2.0 mg

1.6-2.0 mg

50-300 mg

500 mg

Folate (folic acid)

200 mcg

180-400 mcg

400 mcg

No known limit

Vitamin B12

2.0 mcg

1.6-2.0 mcg

5-100 mcg

No known limit

Biotin

30-100 mcg**

30-100 mcg**

300 mcg

No known limit

Pantothenic acid

4-7 mg**

4-7 mg**

10-300 mg

No known limit

Vitamin C

60 mg

60-82 mg

100-2,000 mg#

No known limit

Vitamin D

200 IU

200 IU

400 IU

15,000 IU

Vitamin E

15 IU

12-15 IU

200-600 IU

No known limit

Vitamin K

80 mcg**

65 mcg**

100 mcg

500 mcg

Calcium

1.000-1,200 mg

1,200-1,000 mg

1,200 mg#

2,500 mg

Chromium

50-200 mcg**

50-200 mcg**

50-200 mcg

200 mcg

Copper

1.5-3.0 mg**

1.5-3.0 mg**

3.0 mg

3.0 mg

Iodine

150 mcg

150-187 mcg

150 mcg

2.0 mg

Iron

10 mg

15-30 mg

18 mg

50-100 mg

Magnesium

350 mg

280-337 mg

600 mg

No known limit

Manganese

2.0-5.0 mg**

2.0-5.0- mg**

10 mg

No known limit

Molybdenum

75-250 mcg

75-250 mcg

250 mcg

500 mcg

Phosphorous

800 mg

800-1200 mg

1,200 mg

No known limit

Potassium

2,000 mg†

2,000 mg†

3,500 mg

15,000 mg

Selenium

70 mcg

55-70 mcg

200 mcg

200 mcg

Zinc

15 mg

12-17 mg

30 mg

500 mg


*Lower number in the range is the RDA; higher number is the average of the recommended daily allowances for pregnant and nursing women.
**Estimated safe and adequate daily intake; there is no RDA.
Estimated minimum requirement; there is no RDA.
††Estimated optimal intake based on research showing reduction of disease risk or risk factors for disease. Pregnant women, women attempting pregnancy, or women at risk of unplanned pregnancy must not exceed the RDAs.
†††These upper limits apply only to completely healthy adults who are not pregnant or taking prescription drugs. When a nutrient is marked as "no limit," this should not be taken as license to consume more than the Optimal Adult Intake. Extreme excesses of any one vitamin or mineral can interfere with absorption or use of others (e.g., zinc and copper must be consumed in proper balance). Some individuals may suffer adverse reactions, and there is no benefit to exceeding the Optimal Adult Intake, except to treat or prevent specific disease conditions under expert medical guidance, (e,g, mega--dose niacin for elevated serum cholesterol).
#May cause discomfort or minor side effects at intake levels above the Optimal Adult Intake.

Deficiency risk factors: It is an accepted scientific fact that people have different nutritional needs based on genetics, weight, gender, age, health status, physical activity, and ability to absorb various nutrients. In particular, the RDAs are inadequate for the elderly and people who are ill, immune compromised, or on medication. The elderly are particularly at risk—and indeed many studies indicate that they often don't get the nutrients they need—because they not only absorb nutrients less easily but also consume fewer calories and thus fewer nutrients from food.

Then there are environmental factors. Pollution robs us of vital nutrients and increases our exposure to dangerous toxins, and physical or mental stress (which affects practically everyone these days) also weakens immunity and ups our nutritional needs.

Unfortunately, while our need for vitamins and minerals is only increasing, the nutritional content of our food is decreasing. Even if you eat the full complement of fresh produce, you may be getting far fewer vitamins and minerals than you imagine. Over-farming, over- fertilization, and reduced crop rotation all deplete fruits and vegetables of vital nutrients, as do food processing, refinement, storage, and cooking.

Optimal intake: All nutrients are crucial to good health, although some are needed in larger amounts. Well-formulated multi-vitamin and mineral supplements usually include balanced levels of nutrients at dosages that provide at least the RDA for all age groups. But higher levels of individual nutrients are believed to help prevent specific conditions. Calcium, for example, has been shown to help prevent brittle bones and osteoporosis when taken at levels beyond than the RDA.

Antioxidants such as vitamins A, C, and E, beta-carotene, zinc, copper, manganese, and selenium may provide significant protection from conditions ranging from wrinkles to heart disease and cancer. The amounts of these nutrients needed to provide preventive benefits is often beyond the intake levels obtainable from all but the most ideal diets.

Safety: Talk to your health practitioner before using supplements if you are pregnant or nursing or have an existing health condition. And remember, while more can sometimes be better, that's not always the case. Pay close attention to dosage recommendations and safe amounts for all supplements. Most multi-vitamin/mineral supplements—even high-potency formulas—contain amounts that fall well within the safe dosage range for all but pregnant or lactating women.

No pill or powder can replace the nutritional goodness of whole foods such as fruits, vegetables, and fiber-rich grains, which offer health-promoting, disease-preventive fatty acids and phytochemicals. Supplements are intended, as the name indicates, to supplement a wholesome diet and to fill in the inevitable gaps. But as more and more studies show, they can do much more than that. Nutritional supplements may be our best medicine—the key to a whole new level of wellness.

References
  • Ali N. Nutritionally at-risk groups in the community. Nurs Times 1998 May 20-26;94(20):68-9.
  • Berdanier, C. Advanced Nutrition: Micronutrients. CRC Press, 1998.
  • Block, G. Vitamin C and cancer prevention, American Journal of Clinical Nutrition, 1991 supplement.
  • Bonn D. Vitamin E may reduce prostate-cancer incidence. Lancet 1998 Mar 28;351(9107):961.
  • Brown NA, Bron AJ, Harding JJ, Dewar HM. Nutrition supplements and the eye. Eye 1998;12 ( Pt 1):127-33.
  • Cambridge Heart Antioxidant Study, The Lancet, 1996.
  • Chandra K. Effect of vitamin and trace-element supplementation on immune responses and infection in elderly subjects. The Lancet 1992 Nov 7;340(8828):1124-7.
  • Clark, L. C. et al. Effects of selenium supplementation for cancer prevention, Journal of the American Medical Association, 1996.
  • Gey KF. Vitamins E plus C and interacting conutrients required for optimal health. A critical and constructive review of epidemiology and supplementation data regarding cardiovascular disease and cancer. Biofactors 1998;7(1-2):113-74.
  • Giovannucci, E, et al. Multivitamin use, folate, and colon cancer in women in the Nurses' Health Study. Annals of Internal Medicine, 1998;129:517-524.
  • Hercberg S. [Antioxidant micronutrients and chronic degenerative pathology: the role of complementary nutritional doses]. Bull Mem Acad R Med Belg 1997;152(10-11):379-85; discussion 385-7. [Article in French]
  • Locksmith GJ, Duff P. Preventing neural tube defects: the importance of periconceptional folic acid supplements. Obstet Gynecol 1998 Jun;91(6):1027-34.
  • Losonczy, K.G., et al. Vitamin E and vitamin C supplement use. American Journal of Clinical Nutrition, 1996.
  • Mindell, E. Vitamin Bible, Warner Books.
  • Oakley GP Jr. Eat right and take a multivitamin. N Engl J Med 1998 Apr 9;338(15):1060-1.
  • Rimm, Eric, ScD. Nurses' Health Study, Journal of the American Medical Association, 1998.
  • Robertson, J., et al. A possible role for vitamins C and E in cataract prevention. American Journal of Clinical Nutrition, 1991 supplement.
  • Tufts University Diet & Nutrition Letter, Vol. 12, No. 9 Nov. 1994.
  • United States Department of Agriculture survey, 1987-88.
  • White, E. Relationship between vitamin and calcium supplement use and colon cancer. Cancer Epidemiology: Biomarkers and Prevention, 1997.

 
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